Sour Cream Chicken Enchilada Casserole

If you’re craving something warm, comforting, and packed with flavor, then this Sour Cream Chicken Enchilada Casserole is just what you need! Picture tender, seasoned chicken wrapped in soft tortillas, smothered in a creamy, tangy sour cream sauce, and topped with melted cheese. It’s everything you love about enchiladas but in an easy-to-make casserole form. Trust me, once you take a bite of this, you’ll be hooked—it’s the ultimate comfort food with a Mexican twist!

Whether you’re making it for a busy weeknight dinner, a family gathering, or a potluck, this casserole is a guaranteed crowd-pleaser. The combination of juicy chicken, flavorful seasoning, and that creamy, cheesy sauce will make everyone around the table ask for seconds. Let’s dive into why this dish is a total winner!

Why You’ll Love Sour Cream Chicken Enchilada Casserole

Here’s why this casserole will quickly become a favorite in your recipe rotation:

Easy to Make: No need to roll individual enchiladas. This casserole is straightforward and comes together in one dish, making it perfect for busy weeknights.

Full of Flavor: The creamy sour cream sauce adds a tangy richness, perfectly complementing the seasoned chicken and melted cheese. It’s a flavor explosion in every bite!

Crowd-Pleasing: Whether it’s a family dinner or a party dish, everyone will be reaching for seconds. It’s hearty, satisfying, and can feed a crowd without much effort.

Customizable: Feel free to adjust the spiciness with your favorite salsa or add toppings like jalapeños, cilantro, or avocado to personalize it.

Make-Ahead Friendly: You can prepare this casserole ahead of time and store it in the fridge. When you’re ready to eat, just pop it in the oven!

Ingredients in Sour Cream Chicken Enchilada Casserole

Here’s what you need to make this incredibly flavorful and satisfying casserole:

Cooked Chicken

Shredded rotisserie chicken works perfectly for this recipe—saving you time and adding flavor. You can also cook and shred your own chicken breasts if preferred.

Flour Tortillas

Soft flour tortillas form the base of this casserole. They absorb the creamy sauce and create layers of soft, chewy goodness.

Sour Cream

The star of the creamy sauce! It adds a rich, tangy flavor that perfectly complements the chicken and other ingredients.

Cream of Chicken Soup

This adds extra creaminess and helps bind the casserole together, creating that velvety texture you crave in every bite.

Salsa

A mild or medium salsa gives this casserole a zesty, flavorful kick. It’s the perfect balance of tangy and spicy.

Shredded Cheese

Cheddar and Monterey Jack cheese are the perfect combo for this casserole, creating that irresistible gooey, cheesy top.

Green Chiles (Optional)

For a bit of extra flavor and heat, green chiles can be added to the sauce. It’s optional but highly recommended if you like a little more kick.

Taco Seasoning

This adds a burst of flavor and is the perfect seasoning for the chicken and sauce. You can use a store-bought packet or make your own.

Onion Powder & Garlic Powder

For a bit of extra depth in the sauce.

Salt & Pepper

To taste, to help bring all the flavors together.

Instructions

Ready to dig into this creamy, cheesy casserole? Let’s get started!

Step 1: Preheat the Oven

Preheat your oven to 350°F (175°C). Grease a 9×13-inch baking dish to prevent sticking.

Step 2: Make the Creamy Sauce

In a large bowl, combine sour cream, cream of chicken soup, salsa, green chiles (if using), taco seasoning, onion powder, garlic powder, salt, and pepper. Mix until everything is well combined. This sauce is going to coat every layer and bring all those rich, creamy flavors.

Step 3: Layer the Casserole

Start by spreading a thin layer of the sauce mixture on the bottom of the prepared baking dish. Then, layer 4 flour tortillas on top, slightly overlapping them. Next, spread half of the shredded chicken on top of the tortillas, followed by half of the sauce mixture. Sprinkle with a little bit of the shredded cheese.

Step 4: Repeat the Layers

Add another layer of tortillas, followed by the remaining chicken, sauce, and cheese. You should have two layers of chicken and sauce with tortillas in between. Finish with a generous layer of cheese on top.

Step 5: Bake

Cover the casserole with aluminum foil and bake for about 25 minutes. Then, remove the foil and bake for an additional 10-15 minutes, or until the cheese is melted and bubbly and the casserole is heated through.

Step 6: Serve & Enjoy

Let the casserole sit for about 5 minutes before serving. Garnish with fresh cilantro, jalapeños, or sliced avocado if you like. Serve with a side of rice, beans, or a simple green salad.

Nutrition Facts

Servings: [Number of servings]
Calories per serving: [Calorie count per serving]

Preparation Time

Prep Time: [Time to prepare ingredients]
Cook Time: [Time to cook]
Total Time: [Total time needed]

How to Serve Sour Cream Chicken Enchilada Casserole

• With Rice and Beans: Serve this casserole with Mexican rice and black beans for a complete meal that’s bursting with flavor.
• Top with Fresh Toppings: Garnish with fresh cilantro, avocado slices, or a dollop of sour cream for extra creaminess and freshness.
• Side Salad: A simple side salad with lime dressing and crunchy tortilla chips is a perfect contrast to the creamy casserole.

Additional Tips

• Make Ahead: You can assemble the casserole ahead of time and store it in the fridge for up to 24 hours. When ready to bake, simply preheat the oven and bake as directed.
• Use Different Proteins: If you don’t have chicken, ground beef or turkey would also work wonderfully in this casserole.
• Spice It Up: If you like things spicier, add a diced jalapeño to the sauce or use a hotter salsa.
• Frozen Corn: For added texture and sweetness, toss in some frozen corn kernels between the layers of chicken.

FAQ Section

Q1: Can I use corn tortillas instead of flour tortillas?
A1: Yes, corn tortillas will work, though they may be a little firmer and crispier in texture. Be sure to slightly soften them by warming them in the microwave or on the stove.

Q2: Can I freeze this casserole?
A2: Yes! This casserole freezes really well. After assembling, cover it tightly with foil and freeze for up to 3 months. When ready to bake, thaw it overnight in the fridge and bake as directed.

Q3: Can I use low-fat sour cream?
A3: Absolutely! Low-fat sour cream works just fine in this recipe without sacrificing too much creaminess.

Q4: How do I store leftovers?
A4: Store leftovers in an airtight container in the fridge for up to 3 days. Reheat in the microwave or oven until hot and bubbly.

Q5: Can I make this vegetarian?
A5: Yes! Simply swap the chicken for black beans, grilled veggies, or a meat substitute to make it vegetarian-friendly.

Conclusion

This Sour Cream Chicken Enchilada Casserole is everything you love about Mexican comfort food, but with a twist. It’s creamy, cheesy, and bursting with flavor in every bite. Perfect for feeding a crowd or making ahead for an easy weeknight dinner, this casserole is guaranteed to become a family favorite. So, what are you waiting for? Grab your ingredients and dive into this delicious, cheesy delight!

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